901-10 Demonstration of Blood Flow Through Transmyocardial Laser Channels

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Does blood flow through holmium:YAG transmyocardial laser channels?

BACKGROUND Early reports indicate that transmyocardial laser revascularization improves symptoms in patients with refractory angina. However, there is little experimental evidence of whether blood flow through channels is the mechanism of action. METHODS Endocardial channels were made in the distribution of the left anterior descending coronary artery in canine hearts (n = 5) using a holmium:...

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Laser channels after percutaneous transmyocardial revascularization.

A62-year-old Brazilian white woman with a history of diabetes mellitus had undergone coronary artery bypass grafting to the left anterior descending coronary artery and right coronary artery in 1991. Four years later, she developed recurrent symptoms of angina; angiography revealed occlusion of both saphenous vein grafts. Her native circumflex system remained patent, but her native left anterio...

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Measurement of myocardial blood flow with positron emission tomography before and after transmyocardial laser revascularization.

BACKGROUND Transmyocardial laser revascularization (TMLR) has been proposed for treatment of refractory angina. It has been hypothesized that transmural left ventricular channels created by laser improve myocardial blood flow (MBF) in the treated zones. We aimed to assess the effect of TMLR on MBF and coronary vasodilator reserve (CVR). METHODS AND RESULTS We measured MBF by means of PET with...

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Digital radiographic quantification of myocardial blood flow around a transmyocardial laser channel in rabbit hearts.

BACKGROUND A mechanism underlying the benefits of transmyocardial laser revascularization (TMLR) has been presumed to be improvement in perfusion. We evaluated myocardial blood flow around a laser channel using digital radiography combined with a 3H-labeled desmethylimipramine ([3H]DMI) deposition. METHODS AND RESULTS A laser channel was created in the left ventricular wall using a YAG-laser ...

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Contrast-echocardiography: confirmation of patency of laser channels after transmyocardial laser revascularization.

AIMS Apart from casuistic autopsy results there is no long-term evidence for channel perfusion after transmyocardial laser revascularization in humans. METHODS AND RESULTS Fifteen consecutive patients aged 63+/-17 years were investigated 71+/-15 days after coronary artery bypass surgery and/or transmyocardial revascularization with 13-37 (20+/-5) channels (CO(2) laser, 40 J/pulse). Echocardio...

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ژورنال

عنوان ژورنال: Journal of the American College of Cardiology

سال: 1995

ISSN: 0735-1097

DOI: 10.1016/0735-1097(95)91487-i